Bioscan InVivoScope^TM: Molecular Imaging Suite

The Bioscan InVivoScope^TM software is your magnifying glass in the world of molecular imaging.

2011-04-07 » News: End of life for IVS 1.37 and 1.40

At the end of May, 2011, the IVS branches 1.37 and 1.40 will come to an end. This closes an almost three year development cycle for IVS 1.37 for which by now 6 patch levels have been available. This step retires the Windows-only versions, since IVS became available on Mac OS X with version 1.41 about 18 months ago.

2011-02-14 » News: Patch 4 for InVivoScope 1.42 available

The new patch level for the IVS 1.42 lines comes with three fixes:

• Reorientation: Fixed saving offsets for non-FFP data
• Optimized display of CT with unphysical HU values
• Fixed crash in registration with disabled MIP viewer

2010-11-30 » News: InVivoScope 1.42 patch 2 released

The second maintenance patch for IVS 1.42 fixes a serious bug in memory handling, when multiple large (e.g. CT) datasets are loaded consecutively, where IVS did not fully free memory used for the old dataset before loading the new one. Additionally, the manual viewer and storing HU calibration was fixed on Windows Vista/7. Finally, the support for NanoSPECT-plus CT data was improved.
For a complete list of bugfixes see the Change Log.

2010-09-05 » News: InVivoScope 1.42 released

As of today, we offer the latest version of IVS 1.42. InVivoScope 1.42 is the first version available for both 32- and 64-bit Windows (XP, Vista and 7) as well as Mac OS X (Snow Leopard), removing previous memory barriers when handling large or many datasets. It also improves support for the NanoPET/CT platform. For a complete list of changes and bugfixes see the Change Log.

2009-12-03 » News: InVivoScope 1.41 released

The latest version of IVS is now available as a stable release, coming with three exciting new features:

• Multi-Modal Co-registration
  • Landmark based If you have fiducial markers visible in all modalities of a multi-modal data series, you can now use InVivoScope (namely the Distance Measure tool) to find the transformation required to map one set of points to another one.
    The algorithm already works with a single point (applying simple shift), however, more points help to reduce the degrees of freedom and minimize the error.
    
    
  • Image to image The algorithms provided by this tool allow the co-registration of two images without further knowledge. The basic mode offers simple 3D translations (i.e. shifts as they often occur when using multiple imaging systems) as well as full rigid 3D transformations (which also allows for rotational corrections).
    The optional expert mode, allows the user to chose from a variety of transformations, metrics (cost functions), optimizers and interpolation types to balance speed to quality.
• Multi Planar Reconstruction
  The new MPR view allows to freely rotate and zoom a set of orthogonal slices in 3D. As an alternative to MIP and volume rendering, the new feature allows the user to get an impression of the spacial distribution of radio-activity in the body. All features such as multi-modal co-registration, slice location and color tables are available in this mode. Of course, also this tool allows to store images (locally or as DICOM captures).
• Dockable tools widgets
  All tool (such as VC, MC or DM) as well as all operator windows (such as the cropping form or the quantification table) can now be docked to the main window. Thus, allowing the user more flexibility to arrange arrange the workspace. The old floating style is still supported, and IVS remembers the user's settings in-between sessions.

Please see the ChangeLog for a complete list of changes.
Upgrades to IVS 1.41 are free to all subscribers of a NanoSPECT®, NanoSPECT/CT® or InVivoScope^TM service contract. Please contact your Bioscan sales representative should you have any questions on your qualification for an upgrade.

2009-09-30 » News: InVivoScope 1.40patch1 released

The latest version of the InVivoScope software brings more than 50 bugfixes and improvements. For a full list of changes, please see the Change Log. Major new features include:

• Fix for bug in 1.40: quantification did not take unit into account, leading to wrong factors of 1,000 or 37,000.
• Support for electronic record keeping (21 CFR part 11) with (mandatory) authentication against a Mediso DICOM or inviCRO iPACS server, full DICOM-based audit-trail of all changes, automatic session timeout, etc...
• Full support for Scivis HiSPECT NG (incl. EKG, dynamic and multi-isotope data; and quantification)
• Inverted color tables: quickly invert all color gradients
• Checker board view: easily see quality of co-registration of two modalities
  
• Improved distance measure tool
• Improved support for inviCRO's iPACS preclinical data storage, reporting and workflow tool
• Optimized performance for modern CPUs (about 20% faster than IVS 1.39)
• Improved support for external tools, such as Definiens Developer® and Visage Imaging^TM Amira®

2009-03-12 » News: InVivoScope 1.39 released

The latest IVS release comes with various bugfixes as well as improved support for external systems (MRI, PET, Definiens Segmentation, Amira Analysis) and advanced DICOM features (DICOM captures, multi-time-slot EKG/dynamic files). For a complete list of changes, please see the detailed Change Log.

2008-11-01 » News: InVivoScope 1.38 released

Please find in the download section the new installers for InVivoScope 1.38, the first release fully supporting Mac OS X (Tiger and Leopard). Also new are:

• DataList Manager: Allows you to load as many datasets as fit into your memory, operators like cropping or quantification are applied to the entire list and you can easily select the three datasets you would like to see co-registered (using drag'n'drop in the list or the right click context menu).
• Greatly improved QuantiOp, now allowing summing along all three major axis and data plots (time activity curves)
• Optimized handling of planar data
• Comfortable CroppingOp with input dialog
• Improved CT expert menu and axial voxelsize
• Support for HiSPECT Next generation
• Includes Service Reporter Tool [Windows only]

Please see the Change Log for a complete list of changes.
Upgrade to 1.38 is available at no cost with a valid NanoSPECT®, NanoSPECT/CT® or InVivoScope^TM service contract (you can still continue to use 1.37 including bugfix releases without such a contract).

2008-07-27 » News: InVivoScope 1.37 released

The new IVS 1.37 comes with large number of new features and many bugfixes, of which we would like to mention a few (click on images for further details):

• New Views: Tile View & Multi View
  Added to the well-known orthogonal Slice View we now have two new display options:

  	The Tile View displays a matrix of (e.g. sagittal) slices to give you a quick overview,
  	while the Multi View allows you to compare up to three data sets side by side (here you see a CT, a co-registered and a SPECT data set).

• Automatic CT Bed Removal
  

  Let IVS take care of removing the Minerve animal bed, either directly after reconstruction or on demand. » Example

• Histogram plotting
  

  The new histogram mode allows you to display tabulated frequencies of voxel values.

• Multi-Modality Volume Rendering
  

  Now it is possible to render and fuse the volume of up to three studies/modalities using opacity and gradient maps. Thanks to multi-threading this is still possible in real-time.

For a full list see the Change Log.